Protein Quality Control in Neurodegenerative Diseases.pdf

Protein Quality Control in Neurodegenerative Diseases true
By:Richard I. Morimoto,Yves Christen
Published on 2012-12-13 by Springer Science & Business Media

The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.

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Book which was published by Springer Science & Business Media since 2012-12-13 have ISBNs, ISBN 13 Code is 9783642279287 and ISBN 10 Code is 3642279287

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